Please use this identifier to cite or link to this item: http://docs.prosentient.com.au/prosentientjspui/handle/1/10194
Title: Invasive pneumococcal disease in central Australia.
Authors: Trotman, J
Hughes, B
Mollison, L
Affiliation: Department of Medicine, Alice Springs Hospital, Northern Territory, Australia..
Issue Date: Jun-1995
Citation: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 1995-06; 20(6): 1553-6
Abstract: Invasive pneumococcal disease remains a major problem in certain groups of people. We undertook a hospital-based review of all cases of invasive pneumococcal disease in central Australia over a 2-year period. We observed 79 cases of invasive disease in 78 patients. The incidence of invasive pneumococcal disease was highest in Aborigines under 5 years of age (1,025 cases per 100,000 population per year). The relative risk for Aborigines compared with non-Aborigines was 31.6 (95% CI, 12.8-78.1). Pneumonia was the commonest disease observed (82% of patients). Eight patients died (10.1%), and all of these patients had identifiable risk factors for pneumococcal disease. Serotyping showed that all except two isolates were covered by the existing 23-valent pneumococcal vaccine. These data reveal that Aborigines in central Australia have the highest reported rate of invasive pneumococcal disease in the world. A vaccination program in central Australia should decrease admissions and deaths due to pneumococcal disease.
URI: http://docs.prosentient.com.au/prosentientjspui/handle/1/10194
ISSN: 1058-4838
Type: Journal Article
Subjects: Adolescent
Adult
Australia
Bacterial Vaccines
Child
Child, Preschool
Female
Humans
Incidence
Infant
Male
Middle Aged
Pneumococcal Infections
Risk Factors
Oceanic Ancestry Group
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