Please use this identifier to cite or link to this item: http://docs.prosentient.com.au/prosentientjspui/handle/1/10225
Title: Adverse outcome after incident stroke hospitalization for Indigenous and non-Indigenous Australians in the Northern Territory.
Authors: He, Vincent Y F
Condon, John R
You, Jiqiong
Zhao, Yuejen
Burrow, James N
Affiliation: Menzies School of Health Research, Charles Darwin University, Darwin, NT, Australia..
Menzies School of Health Research, Charles Darwin University, Darwin, NT, Australia..
Department of Health, Northern Territory Government, Darwin, NT, Australia..
Department of Health, Northern Territory Government, Darwin, NT, Australia..
Royal Darwin Hospital, NT Department of Health, Darwin, NT, Australia..
Issue Date: Oct-2015
Citation: International journal of stroke : official journal of the International Stroke Society 2015-10; 10 Suppl A100: 89-95
Abstract: Survival after a stroke is lower for Indigenous than other stroke patients in Australia. It is not known whether recurrence is more common for Indigenous patients, or whether their higher prevalence of comorbidity affects their lower survival. This study aimed to investigate the stroke recurrence and role of comorbidities in adverse stroke outcomes (recurrence and death) for Indigenous compared with other Australians. A retrospective cohort study of first hospitalization for stroke (n = 2105) recorded in Northern Territory hospital inpatient data between 1996 and 2011 was conducted. For the multivariable analyses of adverse outcomes, logistic regression was used for case fatality and competing risk analysis for recurrent stroke and long-term death. Comorbidities (identified from inpatient diagnosis data) were analyzed using the Charlson Comorbidity Index (modified for stroke outcomes). Prevalence of comorbidities, case fatality, incidence of re-hospitalization for recurrent stroke, and long-term death rate were higher for Indigenous than non-Indigenous stroke patients. Adjustment for comorbidity in multivariable analyses considerably reduced Indigenous patients' excess risk for case fatality (odds ratio: 1·25, 0·88-1·78) and long-term death (standard hazard ratio: 1·27, 1·01-1·61) (but not recurrence), implying that their excess risk of death was in part due to higher comorbidity prevalence. Indigenous stroke patients have higher prevalence of comorbidities than non-Indigenous stroke patients, which explained part of the disparity in both case fatality and long-term survival but did not explain the disparity in stroke recurrence at all.
URI: http://docs.prosentient.com.au/prosentientjspui/handle/1/10225
DOI: 10.1111/ijs.12600
Type: Journal Article
Research Support, Non-U.S. Gov't
Subjects: Indigenous Australian
comorbidity
competing risks
hospital data
recurrent stroke
survival analysis
Adult
Age Distribution
Aged
Cohort Studies
Female
Hospitalization
Humans
Incidence
Male
Middle Aged
Northern Territory
Oceanic Ancestry Group
Regression Analysis
Stroke
Population Groups
Appears in Collections:NT Health digital library

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