Please use this identifier to cite or link to this item: http://docs.prosentient.com.au/prosentientjspui/handle/1/10401
Title: Pacific ciguatoxin-1 associated with a large common-source outbreak of ciguatera in east Arnhem Land, Australia.
Authors: Lucas, R E
Lewis, R J
Taylor, J M
Affiliation: Medical Unit, Alice Springs Hospital, Northern Territory, Australia..
Issue Date: 1997
Citation: Natural toxins 1997; 5(4): 136-40
Abstract: We report a retrospective study of the clinical signs and symptoms associated with a point-source outbreak of fish poisoning that occurred with a fish captured from the Arafura Sea, northern Australia. Twenty cases (16 Aboriginal and 4 non-Aboriginal) characteristic of ciguatera, including 4 inpatients and 16 outpatients from the Gove Hospital, were identified based on the pattern of clinical symptoms and signs after ingestion of a large coral cod from a known ciguatera-prone coral reef. In the absence of a serologic test for the victim, laboratory analysis of a 230-g sample of the coral cod (Cephalopolis miniatus), using both mouse bioassay and HPLC/mass spectometry, showed that Pacific ciguatoxin-1 was the principal toxin involved. Intravenous mannitol was administered to one patient without clear benefit. Risk factors for ciguatera poisoning are ingestion of larger portions of reef fish from ciguatera-prone areas. Despite apparent local awareness of the distribution and etiology of the disease, large common-source outbreaks of ciguatera still occur.
URI: http://docs.prosentient.com.au/prosentientjspui/handle/1/10401
DOI: 10.1002/1522-7189(1997)5:4<136::AID-NT2>3.0.CO;2-3
ISSN: 1056-9014
Type: Case Reports
Journal Article
Subjects: Adult
Animals
Australia
Chromatography, High Pressure Liquid
Ciguatoxins
Female
Foodborne Diseases
Humans
Male
Mass Spectrometry
Mice
Retrospective Studies
Ciguatera Poisoning
Disease Outbreaks
Fishes
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