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Title: Impact of results of a rapid Staphylococcus aureus diagnostic test on prescribing of antibiotics for patients with clustered gram-positive cocci in blood cultures.
Authors: Davies, Jane
Gordon, Claire L
Tong, Steven Y C
Baird, Robert W
Davis, Joshua S
Affiliation: Department of Infectious Diseases, Royal Darwin Hospital, Darwin, Australia.
Issue Date: Jun-2012
Citation: Journal of clinical microbiology 2012-06; 50(6): 2056-8
Abstract: In tropical northern Australia, approximately 20% of Staphylococcus aureus bacteremia is caused by methicillin-resistant Staphylococcus aureus (MRSA). We prospectively evaluated the impact on clinician antibiotic prescribing of the results obtained from performing the GeneXpert MRSA/SA test on 151 positive blood cultures with clustered gram-positive cocci. The GeneXpert result led to earlier appropriate prescription of vancomycin for 54% of patients with MRSA; 25% of patients avoided vancomycin, and 16% of patients had all antibiotics ceased.
DOI: 10.1128/JCM.06773-11
Type: Evaluation Studies
Journal Article
Research Support, Non-U.S. Gov't
Subjects: Adult
Anti-Bacterial Agents
Bacteriological Techniques
Diagnostic Tests, Routine
Drug Utilization
Middle Aged
Prospective Studies
Staphylococcal Infections
Staphylococcus aureus
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