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Title: Comorbid Heart Failure and Renal Impairment: Epidemiology and Management.
Authors: Iyngkaran, Pupalan
Thomas, Merlin
Majoni, William
Anavekar, Nagesh S
Ronco, Claudio
Affiliation: Department of Cardiology, Royal Darwin Hospital and Senior Lecturer, Flinders University, Darwin, N.T., Australia..
Issue Date: Dec-2012
Citation: Cardiorenal medicine 2012-12; 2(4): 281-297
Abstract: Heart failure mortality is significantly increased in patients with baseline renal impairment and those with underlying heart failure who subsequently develop renal dysfunction. This accelerated progression occurs independent of the cause or grade of renal dysfunction and baseline risk factors. Recent large prospective databases have highlighted the depth of the current problem, while longitudinal population studies support an increasing disease burden. We have extensively reviewed the epidemiological and therapeutic data among these patients. The evidence points to a progression of heart failure early in renal impairment, even in the albuminuric stage. The data also support poor prescription of prognostic therapies. As renal function is the most important prognostic factor in heart failure, it is important to establish the current understanding of the disease burden and the therapeutic implications.
DOI: 10.1159/000342487
ISSN: 1664-3828
Type: Journal Article
Appears in Collections:NT Health digital library

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