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Title: Surprisingly low seroprevalence of Burkholderia pseudomallei in exposed healthy adults in the Darwin region of tropical Australia where melioidosis is highly endemic.
Authors: James, Gemma L
Delaney, Ben
Ward, Linda
Freeman, Kevin
Mayo, Mark
Currie, Bart J
Affiliation: Emergency Department, Royal Darwin Hospital, Darwin, Northern Territory, Australia..
Issue Date: May-2013
Citation: Clinical and vaccine immunology : CVI 2013-05; 20(5): 759-60
Abstract: In the Darwin region of Australia where melioidosis is highly endemic, only 11/354 (3%) healthy residents were seropositive by indirect hemagglutination assay, despite extensive exposure to Burkholderia pseudomallei. None developed melioidosis, but some described a prior self-limiting illness. This seropositivity rate is much lower than that seen in northeast Thailand, where melioidosis is similarly highly endemic, potentially reflecting important differences between these two locations in the epidemiology of melioidosis.
DOI: 10.1128/CVI.00021-13
Type: Journal Article
Research Support, Non-U.S. Gov't
Subjects: Adult
Antibodies, Bacterial
Burkholderia pseudomallei
Hemagglutination Tests
Middle Aged
Seroepidemiologic Studies
Young Adult
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