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Title: Renal cell metastasis to the thyroid gland: An emerging phenomenon.
Authors: Connolly, Catherine E
Affiliation: General Surgery, Royal Darwin Hospital, Darwin, 0810, Australia. Electronic address:
Issue Date: 2018
Citation: International journal of surgery case reports 2018; 45: 104-106
Abstract: Suspected thyroid malignancies are usually assumed to be primary in origin. Rarely, in 1-3% of cases, the tumour arises from a secondary source such as a melanoma or breast carcinoma. There is a growing body of research concerning metastatic spread of renal cell carcinoma to the thyroid gland. This case report describes the presentation and diagnostic work-up of an 84yr male presenting with a goitre and hoarse voice. Histopathological examination of the excised 95 × 65 × 55 mm tissue mass revealed metastatic clear cell renal cell carcinoma. This disease pattern has become increasingly apparent in recent literature. A literature review of 150 documented cases worldwide showed that the mean interval for this spread to occur is 9 years. There is a need for further investigation into the underlying pathophysiology of this phenomenon and increased awareness from clinicians of its existence.
DOI: 10.1016/j.ijscr.2018.03.032
ISSN: 2210-2612
Type: Journal Article
Subjects: Renal cell carcinoma
Thyroid metastasis
Thyroid nodule
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