Please use this identifier to cite or link to this item: http://docs.prosentient.com.au/prosentientjspui/handle/1/10512
Title: Management of dengue in Australian travellers: a retrospective multicentre analysis.
Authors: Tai, Alex Yc
McGuinness, Sarah L
Robosa, Roselle
Turner, David
Huang, G Khai Lin
Leder, Karin
Korman, Tony M
Thevarajan, Irani
Stewardson, Andrew J
Padiglione, Alexander A
Johnson, Douglas F
Affiliation: Austin Health, Melbourne, VIC alakaytai@gmail.com..
Royal Darwin Hospital, Darwin, NT..
Monash Infectious Diseases, Monash Health and Monash University, Melbourne, VIC..
Victorian Infectious Disease Service, Royal Melbourne Hospital, Melbourne, VIC..
Royal Darwin Hospital, Darwin, NT..
Victorian Infectious Disease Service, Royal Melbourne Hospital, Melbourne, VIC..
Monash Infectious Diseases, Monash Health and Monash University, Melbourne, VIC..
Victorian Infectious Disease Service, Royal Melbourne Hospital, Melbourne, VIC..
Austin Health, Melbourne, VIC..
Monash Infectious Diseases, Monash Health and Monash University, Melbourne, VIC..
Austin Health, Melbourne, VIC..
Issue Date: 17-Apr-2017
Citation: The Medical journal of Australia 2017-04-17; 206(7): 295-300
Abstract: To describe the epidemiology, clinical and laboratory features and outcomes of dengue in returned Australian travellers, applying the revised WHO dengue classification (2009) to this population. Retrospective case series analysis of confirmed dengue cases hospitalised at one of four Australian tertiary hospitals, January 2012 - May 2015. Clinical features, laboratory findings and outcomes of patients with dengue; dengue classification according to 2009 WHO guidelines. 208 hospitalised patients (median age, 32 years; range, 4-76 years) were included in the study. Dengue was most frequently acquired in Indonesia (94 patients, 45%) and Thailand (40, 19%). The most common clinical features were fever (98% of patients) and headache (76%). 84 patients (40%) met the WHO criteria for dengue with warning signs, and one the criteria for severe dengue; the most common warning signs were mucosal bleeding (44 patients, 21%) and abdominal pain (43, 21%). Leukopenia (176 patients, 85%), thrombocytopenia (133, 64%), and elevated liver enzyme levels (154, 76%) were the most common laboratory findings. 46 patients (22%) had serological evidence of previous exposure to dengue virus. WHO guidelines were documented as a management benchmark in ten cases (5%); 46 patients (22%) received non-steroidal anti-inflammatory drugs (NSAIDs). A significant proportion of returning Australian travellers hospitalised for dengue have unrecognised warning signs of severe disease. Many received NSAIDs, which can increase the risk of haemorrhage in dengue. As travel to Asia from Australia continues to increase, it is vital for averting serious outcomes that clinicians can recognise and manage dengue.
URI: http://docs.prosentient.com.au/prosentientjspui/handle/1/10512
Type: Journal Article
Multicenter Study
Subjects: Abdominal Pain
Adolescent
Adult
Aged
Anti-Inflammatory Agents, Non-Steroidal
Australia
Child
Child, Preschool
Dengue
Dengue Virus
Disease Management
Female
Fever
Headache
Hemorrhage
Hospitalization
Humans
Indonesia
Leukopenia
Male
Middle Aged
Retrospective Studies
Tertiary Care Centers
Thailand
Thrombocytopenia
Young Adult
Travel
Appears in Collections:NT Health digital library

Files in This Item:
There are no files associated with this item.


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.