Please use this identifier to cite or link to this item: http://docs.prosentient.com.au/prosentientjspui/handle/1/10674
Title: Pulmonary AL- amyloidosis masquerading as lung malignancy in an Australian Indigenous patient with Sjogren's syndrome.
Authors: Heraganahally, Subash
Digges, Madeline
Haygarth, Madeleine
Liyanaarachchi, Kosala
Kalro, Akash
Mehra, Sumit
Affiliation: Department of Respiratory and Sleep Medicine, Royal Darwin Hospital, Darwin, Australia.. Flinders University, Adelaide, South Australia, Australia..
Department of Respiratory and Sleep Medicine, Royal Darwin Hospital, Darwin, Australia.. Flinders University, Adelaide, South Australia, Australia..
Department of Respiratory and Sleep Medicine, Royal Darwin Hospital, Darwin, Australia..
Department of Anatomical Pathology, Royal Darwin Hospital, Darwin, Australia..
Department of Haematology, Royal Darwin Hospital, Darwin, Australia..
Department of Respiratory and Sleep Medicine, Flinders Medical centre and Flinders University, Adelaide, South Australia, Australia..
Issue Date: 2019
Citation: Respiratory medicine case reports 2019; 26: 94-97
Abstract: Amyloidosis is a heterogeneous group of disorders characterized by misfolding of extracellular proteins. Pulmonary amyloidosis secondary to Sjogren's syndrome (SS) is rare and to the best our knowledge has not been described in indigenous population. There is also minimal information on its clinical and radiological features. We' describe here 52-year-old Australian Indigenous women with underlying Sjogren's syndrome who was initially suspected to have a metastatic lung cancer with FGD avid lung nodule on PET scan. However, wedge resection of the nodule demonstrated eosinophilic homogenous material that demonstrated apple-green birefringence under polarized light after staining with Congo red with immunohistochemistry pattern in keeping with AL amyloidosis.
URI: http://docs.prosentient.com.au/prosentientjspui/handle/1/10674
DOI: 10.1016/j.rmcr.2018.11.015
ISSN: 2213-0071
Type: Journal Article
Subjects: Amyloidosis
Indigenous
Lung nodule
Pulmonary cysts
Sjogren's syndrome
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