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Title: Cerebral mycobacterium avium infection in an HIV-infected patient following immune reconstitution and cessation of therapy for disseminated mycobacterium avium complex infection.
Authors: Murray, R
Mallal, S
Heath, C
French, M
Affiliation: Department of Microbiology, Royal Darwin Hospital, Casuarina, Northern Territory, Australia.
Issue Date: Mar-2001
Citation: European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 2001-03; 20(3): 199-201
Abstract: Reported here is a case of cerebral Mycobacterium avium complex infection that occurred in an HIV-infected patient, who had been treated for disseminated infection and had discontinued clarithromycin and ethambutol following a significant rise in his CD4+ T-cell count after starting highly active antiretroviral therapy. He responded well to excision of the lesion and reinstitution of multidrug therapy. Caution should be exercised when considering ceasing maintenance therapy for disseminated Mycobacterium avium complex infection in HIV-infected patients who demonstrate an apparently good immunologic response to highly active antiretroviral therapy, as this response may not necessarily restore protective immunity against all opportunistic pathogens.
ISSN: 0934-9723
Type: Case Reports
Journal Article
Subjects: AIDS-Related Opportunistic Infections
Antiretroviral Therapy, Highly Active
Brain Diseases
CD4 Lymphocyte Count
Mycobacterium avium-intracellulare Infection
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