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Title: Use of terbinafine for tinea in Australian Aboriginal communities in the Top End.
Authors: Koh, Karen J
Parker, Colin J
Ellis, David H
Pruim, Bert
Leysley, Loyla
Currie, Bart J
Affiliation: Royal Darwin Hospital and Northern Territory Clinical School, Darwin, South Australia, Australia..
Issue Date: Nov-2003
Citation: The Australasian journal of dermatology 2003-11; 44(4): 243-9
Abstract: Tinea of the skin and nails is a common problem in remote Aboriginal communities of the Top End of Australia. A retrospective study was performed on data collected from 104 patients from several indigenous communities. Worksheets were filled in by district medical officers and rural general practitioners, detailing the extent of the tinea. Patients were prescribed between 4 and 12 weeks of 250 mg daily oral terbinafine. Fifty-two patients were followed up, with 45 having a good response to treatment (87%) and with 22 of these patients having full clearance of tinea (42%). A prospective study with 44 subjects was performed. The extent of the tinea was documented and fungal scrapings/clippings were taken. Forty subjects were recruited and given oral terbinafine (2-12 weeks depending on skin/nail involvement) or topical terbinafine if oral treatment was contraindicated. Twenty-five of the 40 (63%) subjects were reviewed. Twenty-three (92%) subjects that were followed up improved clinically, with 8/25 (32%) clearing completely. Twenty (80%) of followed-up patients complied fully with treatment. Terbinafine was found to be a well-tolerated and effective treatment of tinea of the skin and nails.
ISSN: 0004-8380
Type: Comparative Study
Journal Article
Subjects: Administration, Oral
Antifungal Agents
Dose-Response Relationship, Drug
Drug Administration Schedule
Middle Aged
Prospective Studies
Retrospective Studies
Severity of Illness Index
Treatment Outcome
Oceanic Ancestry Group
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