Please use this identifier to cite or link to this item: http://docs.prosentient.com.au/prosentientjspui/handle/1/10924
Title: Multisite Direct Determination of the Potential for Environmental Contamination of Urine Samples Used for Diagnosis of Sexually Transmitted Infections.
Authors: Andersson, Patiyan
Tong, Steven Y C
Lilliebridge, Rachael A
Brenner, Nicole C
Martin, Louise M
Spencer, Emma
Delima, Jennifer
Singh, Gurmeet
McCann, Frances
Hudson, Carolyn
Johns, Tracy
Giffard, Philip M
Affiliation: Division of Global and Tropical Health, Menzies School of Health Research, Charles Darwin University, Tiwi, Northern Territory, Australia..
Division of Global and Tropical Health, Menzies School of Health Research, Charles Darwin University, Tiwi, Northern Territory, Australia..
Division of Global and Tropical Health, Menzies School of Health Research, Charles Darwin University, Tiwi, Northern Territory, Australia..
Division of Global and Tropical Health, Menzies School of Health Research, Charles Darwin University, Tiwi, Northern Territory, Australia..
Royal Darwin Hospital, Tiwi, Australia..
Royal Darwin Hospital, Tiwi, Australia..
Northern Territory Government Sexual Assault Referral Centre (Alice Springs), Australia..
Royal Darwin Hospital, Tiwi, Australia Division of Child Health, Menzies School of Health Research, Charles Darwin University, Tiwi, Australia..
Northern Territory Government Sexual Assault Referral Centre (Darwin), Casuarina Health Service Centre, Casuarina Northern Territory, Australia..
Northern Territory Government Sexual Assault Referral Centre (Alice Springs), Australia..
Northern Territory Government Sexual Assault Referral Centre (Darwin), Casuarina Health Service Centre, Casuarina Northern Territory, Australia..
Division of Global and Tropical Health, Menzies School of Health Research, Charles Darwin University, Tiwi, Northern Territory, Australia..
Issue Date: Sep-2014
Citation: Journal of the Pediatric Infectious Diseases Society 2014-09; 3(3): 189-96
Abstract: The detection of a sexually transmitted infection (STI) agent in a urine specimen from a young child is regarded as an indicator of sexual contact. False positives may conceivably arise from the transfer of environmental contaminants in clinic toilet or bathroom facilities into urine specimens. The potential for contamination of urine specimens with environmental STI nucleic acid was tested empirically in the male and female toilets or bathrooms at 10 Northern Territory (Australia) clinics, on 7 separate occasions at each. At each of the 140 experiments, environmental contamination with Chlamydia trachomatis, Neisseria gonorrhoeae, and Trichomonas vaginalis nucleic acid contamination was determined by swabbing 10 locations, and urine collection was simulated 5 times, using a (1) synthetic urine surrogate and (2) a standardized finger contamination procedure. The most contaminated toilets and bathrooms were in remote Indigenous communities. No contamination was found in the Northern Territory Government Sexual Assault Referral Centre clinics, and intermediate levels of contamination were found in sexual health clinics and in clinics in regional urban centres. The frequency of surrogate urine sample contamination was low but non-zero. For example, 4 of 558 of the urine surrogate specimens from remote clinics were STI positive. This is by far the largest study addressing the potential environmental contamination of urine samples with STI agents. Positive STI tests arising from environmental contamination of urine specimens cannot be ruled out. The results emphasize that urine specimens from young children taken for STI testing should be obtained by trained staff in clean environments, and duplicate specimens should be obtained if possible.
URI: http://docs.prosentient.com.au/prosentientjspui/handle/1/10924
DOI: 10.1093/jpids/pit085
Type: Journal Article
Subjects: contamination
diagnosis
false positive
sexually transmitted infection
urine
Appears in Collections:NT Health digital library

Files in This Item:
There are no files associated with this item.


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.