Please use this identifier to cite or link to this item: http://docs.prosentient.com.au/prosentientjspui/handle/1/11065
Title: Renal fine needle aspiration cytology.
Authors: Zardawi, I M
Affiliation: Department of Pathology, Royal Darwin Hospital, Casuarina, Northern Territory, Australia. ibrahim.zardawi@nt.gov.au.
Abstract: To audit and evaluate the pitfalls in renal fine needle aspiration (FNA) cytology. A retrospective analysis of 180 renal FNAs from 163 patients, encountered at Canberra Hospital, Australian Capital Territory, between June 1989 and July 1997 was undertaken. The FNA procedures had been performed by radiologists under computed tomography (CT) or ultrasound (US) guidance. The study correlated the FNA results with biopsy findings and clinical outcome. The initial cytologic diagnoses included 84 (47%) benign, 6 (3%) atypical, 7 (4%) suspicious, 70 (39%) malignant and 13 (7%) inadequate. Six of the 13 cytologically inadequate group, on further investigation, had malignant histology. The benign cytologic categories contained 79 benign conditions and 5 cases with a malignant outcome. The atypical cytologic group contained 5 benign and 1 malignant case. All nine cytologically suspicious cases had malignant histology. The cytologically malignant group contained 62 malignant, 7 benign and 1 patient lost to follow-up. The sensitivity was 92.5%, specificity was 91.9%, positive predictive value was 89.9%, negative predictive value was 94.0%, and efficacy of the test was 92.2%. Renal FNA can provide an accurate diagnosis in most instances; however, aspiration cytology of the kidney has limitations and pitfalls. Low grade renal cell carcinoma has to be differentiated from oncocytoma, angiomyolipoma, renal infarct and reactive conditions. Renal FNA has a high negative predictive value, which is useful in reassuring patients with radiologically and cytologically benign lesions. Negative FNA does not exclude malignancy in the presence of a radiologic suspicion.
URI: http://docs.prosentient.com.au/prosentientjspui/handle/1/11065
DOI: 10.1159/000330974
ISSN: 0001-5547
Type: Journal Article
Subjects: Adult
Aged
Biopsy, Needle
Carcinoma, Large Cell
Carcinoma, Renal Cell
False Positive Reactions
Female
Follow-Up Studies
Humans
Kidney Neoplasms
Leiomyosarcoma
Male
Middle Aged
Predictive Value of Tests
Retrospective Studies
Sensitivity and Specificity
Appears in Collections:NT Health digital library

Files in This Item:
There are no files associated with this item.


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.