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|Title:||Spontaneous cerebrospinal fluid rhinorrhoea and aspiration pneumonitis following initiation of continuous positive airway pressure treatment for obstructive sleep apnoea.|
|Authors:||Wasgewatta, Sanjiwika Lalanjani|
Heraganahally, Subash Shanthakumar
|Affiliation:||Department of Respiratory and Sleep Medicine Royal Darwin Hospital Darwin Northern Territory Australia..|
Department of Medical Imaging Royal Darwin Hospital Darwin Northern Territory Australia.. Department of Medical Imaging, Florey Institute of Neuroscience Melbourne Victoria Australia..
Department of General Surgery/Neurosurgery Royal Darwin Hospital Darwin Northern Territory Australia..
Department of General Medicine Royal Darwin Hospital Darwin Northern Territory Australia..
Department of Respiratory and Sleep Medicine Royal Darwin Hospital Darwin Northern Territory Australia.. College of Medicine and Public Health, Flinders University Adelaide South Australia Australia.. Northern Territory Medical School Charles Darwin University Darwin Northern Territory Australia..
|Citation:||Respirology case reports 2019-08; 7(6): e00435|
|Abstract:||Continuous positive airway pressure (CPAP) therapy is very often the treatment of choice for obstructive sleep apnoea (OSA). The association between intracranial hypertension and spontaneous cerebrospinal fluid (CSF) rhinorrhoea is being increasingly recognized among patients with OSA. However, spontaneous CSF rhinorrhoea following initiation of CPAP therapy for OSA is very rarely documented in the literature. In this report, we describe a 53-year-old woman with severe OSA who, while being evaluated for possible intracranial hypertension, developed spontaneous CSF rhinorrhoea and CSF aspiration pneumonitis as a complication of CPAP therapy. Magnetic resonance imaging confirmed fluid tracks at the skull base, and a nasal swab demonstrated positive β2-transferrin. Computer tomography (CT) chest showed findings consistent with CSF aspiration pneumonitis. Resolution of both CSF leak and pneumonitis were noted following treatment with azetozolamide and curative endoscopic trans-nasal surgery along with ventriculoperitoneal shunt.|
continuous positive airway pressure
obstructive sleep apnoea
|Appears in Collections:||NT Health digital library|
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