Please use this identifier to cite or link to this item: http://docs.prosentient.com.au/prosentientjspui/handle/1/11298
Title: Spontaneous cerebrospinal fluid rhinorrhoea and aspiration pneumonitis following initiation of continuous positive airway pressure treatment for obstructive sleep apnoea.
Authors: Wasgewatta, Sanjiwika Lalanjani
Manning, Nathan
Redmond, Michael
Howard, Diane
Heraganahally, Subash Shanthakumar
Affiliation: Department of Respiratory and Sleep Medicine Royal Darwin Hospital Darwin Northern Territory Australia..
Department of Medical Imaging Royal Darwin Hospital Darwin Northern Territory Australia.. Department of Medical Imaging, Florey Institute of Neuroscience Melbourne Victoria Australia..
Department of General Surgery/Neurosurgery Royal Darwin Hospital Darwin Northern Territory Australia..
Department of General Medicine Royal Darwin Hospital Darwin Northern Territory Australia..
Department of Respiratory and Sleep Medicine Royal Darwin Hospital Darwin Northern Territory Australia.. College of Medicine and Public Health, Flinders University Adelaide South Australia Australia.. Northern Territory Medical School Charles Darwin University Darwin Northern Territory Australia..
Issue Date: Aug-2019
Citation: Respirology case reports 2019-08; 7(6): e00435
Abstract: Continuous positive airway pressure (CPAP) therapy is very often the treatment of choice for obstructive sleep apnoea (OSA). The association between intracranial hypertension and spontaneous cerebrospinal fluid (CSF) rhinorrhoea is being increasingly recognized among patients with OSA. However, spontaneous CSF rhinorrhoea following initiation of CPAP therapy for OSA is very rarely documented in the literature. In this report, we describe a 53-year-old woman with severe OSA who, while being evaluated for possible intracranial hypertension, developed spontaneous CSF rhinorrhoea and CSF aspiration pneumonitis as a complication of CPAP therapy. Magnetic resonance imaging confirmed fluid tracks at the skull base, and a nasal swab demonstrated positive β2-transferrin. Computer tomography (CT) chest showed findings consistent with CSF aspiration pneumonitis. Resolution of both CSF leak and pneumonitis were noted following treatment with azetozolamide and curative endoscopic trans-nasal surgery along with ventriculoperitoneal shunt.
URI: http://docs.prosentient.com.au/prosentientjspui/handle/1/11298
DOI: 10.1002/rcr2.435
ORCID: https://orcid.org/0000-0003-0788-7137
ISSN: 2051-3380
Type: Case Reports
Subjects: Aspiration pneumonitis
cerebrospinal fluid
continuous positive airway pressure
intracranial hypertension
obstructive sleep apnoea
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