Please use this identifier to cite or link to this item: http://docs.prosentient.com.au/prosentientjspui/handle/1/11313
Title: Plasmodium knowlesi malaria during pregnancy.
Authors: Barber, Bridget E
Bird, Elspeth
Wilkes, Christopher S
William, Timothy
Grigg, Matthew J
Paramaswaran, Uma
Menon, Jayaram
Jelip, Jenarun
Yeo, Tsin W
Anstey, Nicholas M
Affiliation: Menzies School of Health Research, Charles Darwin University, Infectious Diseases Society Sabah-Menzies School of Health Research Clinical Research Unit..
Infectious Diseases Society Sabah-Menzies School of Health Research Clinical Research Unit..
Infectious Diseases Society Sabah-Menzies School of Health Research Clinical Research Unit..
Infectious Diseases Society Sabah-Menzies School of Health Research Clinical Research Unit Infectious Diseases Unit..
Menzies School of Health Research, Charles Darwin University, Infectious Diseases Society Sabah-Menzies School of Health Research Clinical Research Unit..
Menzies School of Health Research, Charles Darwin University, Infectious Diseases Society Sabah-Menzies School of Health Research Clinical Research Unit..
Department of Medicine, Clinical Research Centre, Queen Elizabeth Hospital..
Sabah Department of Health, Kota Kinabalu, Malaysia..
Menzies School of Health Research, Charles Darwin University, Infectious Diseases Society Sabah-Menzies School of Health Research Clinical Research Unit Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore..
Menzies School of Health Research, Charles Darwin University, Royal Darwin Hospital, Australia Infectious Diseases Society Sabah-Menzies School of Health Research Clinical Research Unit..
Issue Date: 1-Apr-2015
Citation: The Journal of infectious diseases 2015-04-01; 211(7): 1104-10
Abstract: Plasmodium knowlesi is the commonest cause of malaria in Malaysia, but little is known regarding infection during pregnancy. To investigate comparative risk and consequences of knowlesi malaria during pregnancy, we reviewed (1) Sabah Health Department malaria-notification records created during 2012-2013, (2) prospectively collected data from all females with polymerase chain reaction (PCR)-confirmed malaria who were admitted to a Sabah tertiary care referral hospital during 2011-2014, and (3) malaria microscopy and clinical data recorded at a Sabah tertiary care women and children's hospital during 2010-2014. During 2012-2013, 774 females with microscopy-diagnosed malaria were notified, including 252 (33%), 172 (20%), 333 (43%), and 17 (2%) with Plasmodium falciparum infection, Plasmodium vivax infection, Plasmodium malariae/Plasmodium knowlesi infection, and mixed infection, respectively. Among females aged 15-45 years, pregnancy was reported in 18 of 124 (14.5%), 9 of 93 (9.7%), and 4 of 151 (2.6%) P. falciparum, P. vivax, and P. malariae/P. knowlesi notifications respectively (P = .002). Three females with knowlesi malaria were confirmed as pregnant: 2 had moderate anemia, and 1 delivered a preterm low-birth-weight infant. There were 17, 7, and 0 pregnant women with falciparum, vivax, and knowlesi malaria, respectively, identified from the 2 referral hospitals. Although P. knowlesi is the commonest malaria species among females in Sabah, P. knowlesi infection is relatively rare during pregnancy. It may however be associated with adverse maternal and pregnancy outcomes.
URI: http://docs.prosentient.com.au/prosentientjspui/handle/1/11313
DOI: 10.1093/infdis/jiu562
Type: Journal Article
Research Support, Non-U.S. Gov't
Subjects: Plasmodium knowlesi
malaria
maternal anemia
pregnancy
preterm delivery
Adolescent
Adult
Anemia
DNA, Protozoan
Disease Notification
Female
Geography
Humans
Malaria
Malaysia
Middle Aged
Plasmodium knowlesi
Polymerase Chain Reaction
Pregnancy
Pregnancy Complications, Parasitic
Prospective Studies
Tertiary Care Centers
Young Adult
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